Itsuwa Yozakura was the fifth head of the Yozakura Family. Itsuwa ran the Yozakura Silk Mill during its prime and used the fibers produced to launch multiple brands and shows. This led to the rise of the Yozakura Zaibatsu Conglomerate.She also developed the Pumped-up Manju bun, an elixir used to lessen the strain Someinine has on the body. (Source: Mission: Yozakura Family Wiki)